Pain

💊 Behandelingen bij pain

Gerangschikt op onderbouwing (aantal onafhankelijke bronnen) en gerapporteerde frequentie.

+ Vrij verkrijgbaar bij ons

• +Naproxen4 bronnen🟠Aleve Comp 24€ 8,00
  About the substance

  Non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting the enzyme cyclooxygenase (COX), leading to reduced synthesis of prostaglandins.

  Dosage: 1 tablet twice daily, preferably taken with water at least 30 minutes before a meal.
• +Acetaminophen4 bronnen🟠Paracetamol Kruidvat Health 500mg Comp 20€ 1,85
  About the substance

  Analgesic and antipyretic from the anilide group. Its mechanism of action is based on the inhibition of cerebral prostaglandin synthesis and counteracting the effect of endogenous pyrogens on the hypothalamus.

  Dosage: 10 to 15 mg/kg of body weight per dose, with a maximum of 60 mg/kg per day; at least 4 hours between doses.
• +Ibuprofen4 bronnen🟠Ibuprofen Ab 200mg Filmomh Tabl 24€ 3,90🟠Ibuprofen Sandoz 200mg Filmomh Tabl 30€ 4,95🟠Nurofen Kind 200mg Filmomh Tabl 24 Verv.2475739€ 5,14Meer uit 42 →
  About the substance

  Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) that acts as a non-selective inhibitor of the cyclooxygenase enzyme, leading to reduced synthesis of prostaglandins.

  Dosage: For patent ductus arteriosus: 3 intravenous injections at 24-hour intervals (1st dose 10 mg/kg, 2nd and 3rd dose 5 mg/kg). For pain/fever in adults and children >12 years: every 4-6 hours if needed.
• +Dextrose2 bronnen🟠Heparon Junior 400g€ 19,02
• +Glycerin2 bronnen🟠Phlexy-vits Tabl 60x1,7g€ 49,03🟠Gte Olie 1l€ 1.069,68
  About the substance

  Osmotic laxative that draws water into the bowel and mildly stimulates the intestinal mucosa, leading to accelerated bowel transit.

  Dosage: Adults: 1 to 2 suppositories per day; children < 6 years: 1-1.7 grams rectally; administer as needed.
• +Aspirin2 bronnen🟠Sedergine 325mg Bruistabl 20 Nf€ 3,09
  About the substance

  Non-selective cyclooxygenase (COX) inhibitor that blocks the synthesis of prostaglandins and thromboxanes, leading to analgesic, antipyretic, anti-inflammatory, and antiplatelet effects.

  Dosage: Pain/fever: every 4 to 6 hours as needed. Cardiovascular prevention: usually once daily.

+ Enkel op voorschrift — bespreek met je arts

• +Mefenamic Acid5 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  A non-steroidal anti-inflammatory drug (NSAID) that acts as an inhibitor of the cyclooxygenase enzyme, thereby blocking the synthesis of prostaglandins.

  Dosage: Take every 6 hours with food, for a maximum of 1 week.
• +Etodolac5 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  A non-steroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin synthesis by inhibiting cyclooxygenase enzymes.

  Dosage: Arthritis: 2-3 times daily tablets/capsules or once daily extended-release. Pain: every 6 to 8 hours.
• +Amitriptyline Hydrochloride4 bronnenop voorschrift — vraag je arts
  About the substance

  Tricyclic antidepressant that inhibits the reuptake of norepinephrine and serotonin, and also possesses ion channel blocking effects (sodium, potassium, NMDA) and anticholinergic properties.

  Dosage: Adults (depression): starting dose 25 mg twice daily, gradually increased to a maximum of 150 mg per day.
• +Diflunisal4 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  A salicylate derivative and non-steroidal anti-inflammatory drug (NSAID) that inhibits pain, inflammation, and fever by inhibiting prostaglandin synthesis via the arachidonic acid pathway.

  Dosage: Take tablets every 8 to 12 hours with water, milk, or food; swallow whole without chewing or crushing.
• +Nefopam Hydrochloride3 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Non-opioid analgesic with a unique mechanism of action that acts as a central monoamine reuptake inhibitor (serotonin, norepinephrine, and dopamine).
• +Tiaprofenic acid3 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Tiaprofenic acid belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs). It blocks the enzymes cyclooxygenase-1 and -2, thereby inhibiting the production of prostaglandins. Because prostaglandins are mediators of pain, fever, and inflammation, this inhibition leads to a decrease in swelling, redness, and pain.
• +Diclofenac Potassium4 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Non-steroidal anti-inflammatory drug (NSAID) that inhibits the enzymes cyclooxygenase (COX)-1 and -2, thereby blocking the synthesis of prostaglandins (mediators of pain and inflammation).

  Dosage: For cataract surgery: 1 drop 4 times daily, starting 24 hours after surgery for 2 weeks. For refractive surgery: 1 hour before surgery, 15 minutes after surgery, then 4 times daily for a maximum of 3 days.
• +Hydrocodone4 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Synthetic opioid derivative of codeine that acts as an agonist on opioid receptors in the central nervous system.

  Dosage: Immediate-release forms: every 4-6 hours; long-acting forms: every 12 hours.
• +Ketorolac Tromethamine3 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Ketorolac is a non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting cyclooxygenase enzymes, leading to reduced synthesis of prostaglandins responsible for pain and inflammation.

  Dosage: Systemic: lowest possible dose, maximum 5 days. Ophthalmic: 1 drop 3 times daily, starting 24 hours before surgery until 3 weeks after.
• +Nabumetone3 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Non-steroidal anti-inflammatory drug (NSAID) that acts as a prodrug; the active metabolite 6-methoxy-2-naphthylacetic acid inhibits cyclooxygenase (COX) enzymes, leading to reduced prostaglandin biosynthesis.

  Dosage: Adults and children from 14 years: 1 g once daily at bedtime. For acute complaints: starting dose of 1 g, followed by 1 g at bedtime. For severe symptoms: temporarily (max. 15 days) an extra 1 g in the morning.
• +Esflurbiprofen2 bronnenniet vrij verkrijgbaar — vraag je arts
• +Phenazopyridine3 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  A urinary tract analgesic that acts as an azo dye and has a local anesthetic effect on the mucous membrane of the lower urinary tract.

  Dosage: 1 tablet 3 times a day after meals, for a maximum of 2 days.
• +Ketoprofen3 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) from the propionic acid derivative group. It works by inhibiting the enzyme cyclooxygenase (COX), leading to reduced synthesis of prostaglandins, which are the mediators of pain, fever, and inflammation.

  Dosage: 25 mg 1–3 times daily; if necessary, start with 50 mg; maximum 100 mg per day. Take during meals with a glass of water.
• +Anileridine2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Synthetic opioid analgesic that acts as an agonist on opioid receptors in the central nervous system (CNS) to suppress pain perception.
• +Bupivacaine hydrochloride2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  An amide-type local anesthetic that blocks sodium channels in nerve fibers, interrupting the conduction of pain signals and motor impulses.

  Dosage: Depending on the technique and patient factors; consult standard reference works for specific dosage schedules.
• +Propyphenazone2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Propyphenazone is a pyrazolone derivative with analgesic and antipyretic properties. It inhibits the synthesis of prostaglandins in the central nervous system by interacting with the enzyme cyclooxygenase. This raises the pain threshold and influences the thermoregulatory center in the hypothalamus to lower body temperature.
• +Sodium salicylate2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Non-steroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase enzymes, leading to a reduced synthesis of prostaglandins.
• +Tiropramide2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Tiropramide is an antispasmodic that relaxes smooth muscles by lowering the intracellular calcium concentration. Unlike classic anticholinergics, it does not work via muscarinic receptors, but directly on the muscle cell membrane. This reduces the contraction force and frequency of cramps without significantly affecting salivation or heart rate.
• +Nitrous Oxide 98 % Gas2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Other general anesthetic that induces analgesic effects via opioid receptors and achieves anesthesia through modulation of GABA and glutamate (NMDA) receptors.

  Dosage: Inhalation via spontaneous ventilation; administration may last a maximum of 60 minutes.
• +Ziconotide2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Ziconotide is an N-type calcium channel-blocking peptide. By inhibiting these channels in neurons, the release of nociceptive neurotransmitters in the dorsal horn of the spinal cord is blocked, leading to a powerful analgesic effect.

  Dosage: Continuous intrathecal infusion: starting dose maximum 2.4 mcg/day. Titration in steps of maximum 2.4 mcg/day at intervals of at least 24-48 hours. Maximum dose 21.6 mcg/day.
• +Rofecoxib3 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Selective COX-2 inhibitor (prostaglandin G/H synthase 2 inhibitor) that inhibits the synthesis of prostaglandins.

  Dosage: Oral doses of 12.5 mg, 25 mg, and 50 mg.
• +Capsaicin3 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Highly selective agonist for the TRPV1 receptor (transient receptor potential vanilloid 1). The mechanism relies on initial activation of nociceptors followed by desensitization, making them less sensitive to stimuli.

  Dosage: Apply a maximum of 4 patches to intact, dry skin by a healthcare professional; application time 30 minutes for the feet and 60 minutes for other body parts.
• +Etidocaine2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Etidocaine is an injectable amide-type local anesthetic that blocks nerve conduction by stabilizing sodium channels in the nerve cell membrane.
• +Ethyl chloride2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  A local anesthetic that causes an intense cold effect on the skin through rapid evaporation, thereby blocking nerve conduction.
• +Levorphanol2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Levorphanol is a potent synthetic opioid that acts as a strong agonist at both mu- and kappa-opioid receptors. It blocks the transmission of pain signals in the central nervous system and alters the perception of pain. It has a longer duration of action than many other opioids due to its pharmacokinetic properties.
• +Dyclonine2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Dyclonine is a local anesthetic that blocks the conduction of nerve impulses by reducing the permeability of the neuronal membrane to sodium ions.
• +Dexketoprofen2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Non-steroidal anti-inflammatory drug (NSAID) that inhibits pain, inflammation, and fever by inhibiting the cyclooxygenase enzyme, which leads to reduced synthesis of prostaglandins from arachidonic acid.

  Dosage: Oral: 12.5 mg 4-6 times daily or 25 mg 3 times daily (max. 75 mg/day, 30 min before meals). Injection/infusion: 50 mg every 8-12 hours (max. 150 mg/day, max. 2 days).
• +Etoricoxib2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Etoricoxib is a selective cyclooxygenase-2 (COX-2) inhibitor that reduces the synthesis of prostaglandins from arachidonic acid.

  Dosage: Osteoarthritis: 30 mg once daily (max. 60 mg). Rheumatoid arthritis: 60 mg once daily (temporarily max. 90 mg). Use the lowest effective dose for the shortest possible duration.
• +Gabapentin3 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Gabapentin is an antiepileptic drug that binds to the α2δ subunit of voltage-gated calcium channels in the central nervous system, thereby modulating neurotransmission.

  Dosage: Starting schedule for adults/adolescents (≥12 years): day 1: 300 mg once daily, day 2: 300 mg twice daily, day 3: 300 mg three times daily. Discontinue by gradually tapering over at least 1 week.
• +Salicyclic acid2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Keratolytic, bacteriostatic, and fungicidal agent that dissolves intercellular connections in the epidermis, causing the horny layer to shed.

  Dosage: Depending on the condition and the product; follow the instructions on the label or the doctor's prescription strictly.
• +Prilocaine2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Amide-type local anesthetic that reversibly inhibits the excitability of nerve fibers and pain receptors by affecting ion permeability.

  Dosage: For hospital use only by specialized medical personnel; dosage depends on the chosen anesthetic technique.
• +Ketoprofen 2.5% Topical2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) from the propionic acid derivative group. It works by inhibiting the enzyme cyclooxygenase (COX), leading to reduced synthesis of prostaglandins, which are the mediators of pain, fever, and inflammation.

  Dosage: 25 mg 1–3 times daily; if necessary, start with 50 mg; maximum 100 mg per day. Take during meals with a glass of water.
• +Alefacept2 bronnenop voorschrift — vraag je arts
  About the substance

  Immunosuppressive dimeric fusion protein that blocks the interaction between LFA-3 and CD2, thereby inhibiting the activation and proliferation of T-lymphocytes.

  Dosage: One intramuscular or intravenous injection per week for 12 weeks; a second 12-week cycle is possible after a break of at least 12 weeks.
• +Valdecoxib2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Selective COX-2 inhibitor (NSAID) that inhibits the synthesis of prostaglandins through selective inhibition of the cyclooxygenase-2 enzyme.
• +Tenoxicam2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Non-steroidal anti-inflammatory drug (NSAID) that acts as a potent inhibitor of cyclooxygenase-1 (COX-1) and -2 (COX-2) enzymes, thereby blocking the biosynthesis of prostaglandins.

  Dosage: 20 mg once daily, to be taken with a glass of water during a meal.
• +Methadone2 bronnenop voorschrift — vraag je arts
  About the substance

  Synthetic opioid analgesic that acts as a full mu-opioid receptor agonist and NMDA receptor antagonist. Through this combination, it mimics endogenous opioids for pain relief and dampens excitatory pain pathways in the central nervous system.

  Dosage: For pain: 5 to 10 mg intravenously or intramuscularly every 6 to 8 hours. For withdrawal, the dosage is individual and not standardized.
• +Dexibuprofen2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Dexibuprofen is the active S(+)-isomer of ibuprofen. It is an NSAID that inhibits the production of prostaglandins by blocking cyclooxygenase enzymes. Because it is the active form, a lower dosage is required than with the racemic mixture to achieve the same anti-inflammatory and analgesic effect.
• +Cyclobenzaprine2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Centrally acting muscle relaxant with a structure related to tricyclic antidepressants; it works by influencing motor activity in the brainstem.

  Dosage: Tablets: 2-4 times daily; extended-release capsules: 1-2 times daily. Maximum duration of use: 3 weeks.
• +Piroxicam2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Piroxicam is a non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting the cyclooxygenase enzyme, leading to reduced synthesis of prostaglandins.

  Dosage: The maximum recommended daily dose is 20 mg.
• +Meloxicam2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Non-steroidal anti-inflammatory drug (NSAID) of the oxicam class, which acts as a preferential COX-2 inhibitor by blocking the biosynthesis of prostaglandins.

  Dosage: 7.5 mg per day, to be taken as a single daily dose.
• +Pregabalin2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Pregabalin is a gamma-aminobutyric acid analog that binds to the α2δ-subunit of voltage-dependent calcium channels in the central nervous system, thereby reducing calcium influx and the release of excitatory neurotransmitters.

  Dosage: 150 to 600 mg per day, divided into two or three doses.
• +Salicylamide2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Salicylamide is a derivative of salicylic acid with analgesic and antipyretic properties. It works by inhibiting the synthesis of prostaglandins in the central nervous system. It is often combined with other substances to enhance the analgesic effect.
• +Naloxone2 bronnenop voorschrift — vraag je arts
  About the substance

  Naloxone is a competitive opioid antagonist with high affinity for μ-opioid receptors, where it acts as an inverse agonist to displace and block the effects of opioids.

  Dosage: Available as nasal spray, intramuscular, intravenous, or subcutaneous injection for emergency therapy; dosage depends on the clinical situation and route of administration.
• +Sulindac2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Non-steroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class; it is a prodrug that inhibits prostaglandin synthesis by inhibiting COX-1 and COX-2.

  Dosage: Take twice daily with food at fixed times.
• +Celecoxib2 bronnenop voorschrift — vraag je arts
  About the substance

  Celecoxib is a selective cyclo-oxygenase-2 (COX-2) inhibitor from the class of non-steroidal anti-inflammatory drugs (NSAIDs). It works by inhibiting the synthesis of prostaglandins via selective blockade of the COX-2 enzyme, leading to a reduction in pain and inflammation.

  Dosage: Osteoarthritis: 200 mg once daily or 100 mg twice daily. Rheumatoid arthritis and ankylosing spondylitis: 100 mg twice daily. If necessary, increase to 200 mg twice daily.
• +Baclofen2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Baclofen is a GABA-β receptor agonist that acts as a centrally acting spasmolytic. By stimulating these receptors in the spinal cord, it suppresses mono- and polysynaptic reflex transmission, leading to muscle relaxation.

  Dosage: The dosage is strictly individual and requires titration; for intrathecal administration, a test phase via bolus injection is started, followed by continuous infusion via an implantable pump.
• +Codeine2 bronnenop voorschrift — vraag je arts
  About the substance

  A natural opium alkaloid and opioid analgesic that acts as a central antitussive by suppressing the cough center and as an antiperistaltic agent.

  Dosage: Adults: 10 mg every 4 to 6 hours (max. 120 mg/day). Children 12-18 years: 10 mg 4 times daily (max. 1 mg/kg/day). Oral use.
• +Indomethacin2 bronnenop voorschrift — vraag je arts
  About the substance

  Indomethacin is a non-steroidal anti-inflammatory drug (NSAID) that works through potent, non-selective inhibition of the enzyme cyclooxygenase (COX), thereby blocking the synthesis of prostaglandins and thromboxane.

  Dosage: Capsules/suspension: 2-4x daily; extended-release capsules: 1-2x daily; suppositories: 2-4x daily. Preferably taken with food or antacids.
• +Magnesium Sulfate2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Magnesium sulfate acts as an osmotic laxative that accelerates bowel transit. In diagnostic use, it ensures rapid emptying of the bowels, making the mucosa more visible during imaging. It increases fluid retention in the intestine, which cleanses the intestinal wall.
• +Lidocaine2 bronnenniet vrij verkrijgbaar — vraag je arts
  About the substance

  Lidocaine is a class IB antiarrhythmic and local anesthetic that blocks sodium channels, thereby stabilizing the membrane, reducing automaticity in the heart, and suppressing conduction in nerve tissue.

  Dosage: Individual dosage under ECG monitoring; in case of shock, heart failure, or liver failure, significantly reduce the dose.

Bron: dis-treat master (BCFI/itreat · EMA · SIDER · FAERS-frequentie). Geen diagnose — dit vervangt geen consult.